Kevin B. Mahoney is chief executive officer of the University of Pennsylvania Health System, a pillar of the Penn Medicine enterprise. He leads health system operations, spanning six hospitals, multispecialty centers and hundreds of outpatient facilities in Pennsylvania, Delaware, and New Jersey.

Penn Medicine consists of the University of Pennsylvania Health System and the Perelman School of Medicine. Together, they form one of the world’s leading—and America’s oldest—academic medical centers dedicated to the related missions of medical education, biomedical research, and excellence in patient care.

Mahoney joined Penn Medicine in 1996, holding leadership posts for nearly three decades. Before his appointment as CEO in July 2019, he served as executive vice president and chief administrative officer of the University of Pennsylvania Health System and as executive vice dean of the Perelman School of Medicine.

At Penn Medicine, Mahoney has led initiatives focused on improving patient experience and care efficiency in treatment settings. These include the recent creation of the Pavilion, a 1.5-million-square-foot, future-forward hospital, and the unification of the health system’s hospitals, clinics, and home care programs under one shared electronic health records platform.

Drawing from lessons learned during the COVID-19 pandemic, Mahoney has created a blueprint for meeting patients when and where they need care. In this approach, care is delivered across four sites: in a hospital, at a multispecialty center, in the home, or through telehealth. The approach is leading to better patient experiences, reduced hospitalizations, shorter inpatient stays, and decreased health costs, all of which ultimately help people live longer, healthier lives.

An advocate for access and equity, Mahoney co-launched a partnership with the Wharton School of the University of Pennsylvania to invest funds into organizations focused on strengthening the social determinants of health. To date, the Fund for Health has contributed $1.6 million to early-stage businesses.

Mahoney has contributed to The New England Journal of Medicine, the Journal of the American Medical Association, and The Philadelphia Inquirer, offering perspectives on health equity, access to quality care, social justice, and more. He has been named one of the “100 Most Influential People in Health Care” by Modern Healthcare, one of “100 Most Influential People in Philadelphia” by Philadelphia Magazine, and one of the “Most Admired CEOs” by the Philadelphia Business Journal.

A graduate of Millersville State College in Millersville, Pennsylvania, Mahoney earned a bachelor’s degree in economics. He also holds an MBA and a doctorate from the Fox School of Business at Temple University in Philadelphia.